Techbio — a model of pathogen biology

The AI that predicts and designs the response to biological threats.

genome in → countermeasure out → designed next

Subsira builds models that predict what defeats a pathogen — and ultimately design it.

~1,000,000 measured genome × countermeasure pairs Multimodal · phages, peptides, proteins, small molecules
subsira · predict
Threat unresolved
Input — pathogen genome
E. coli · ST131 ✕ no shelf option holds
ATGCTAGCGGATCCTAGCTAGGCTAAGCTTGACCTAGCGTTAGCCGATCGGATCGTAGCTAGCGATCGATCGGCTAGCTAGCGGATCC
Scoring countermeasures against this genome…
Predicted countermeasures — all modalities
  • 01vB_Eco-217 · phagetop
  • 02SB-pep-0412 · peptidealt
  • 03SB-prot-118 · proteinalt
  • 04SB-sm-0937 · small moleculealt
  • 05de novo candidate · designednext
predicted from the genome alone
The gap

AI can read and write biology. Nothing tells us what defeats it.

Pathogens evolve faster than we can respond — and AI, now able to design new biology, is widening the gap.

Why it's hard

The bottleneck isn't data or models. It's labels.

01 · Abundant

Genomes

Cheap, routine, and piling up in public archives.

02 · Powerful

Models

Already capable of learning biology at this scale.

03 · Scarce

Labels

The bottleneck. Never recorded at scale, and impossible to scrape.

"Will countermeasure X defeat pathogen Y?"

So we generate them ourselves.

The asset

The labels are the moat.

~1,000,000
genome × countermeasure pairs, measured in-house
3,000+
clinical isolates
500+
countermeasures, across four modalities

Genomes are downloadable. Models are reproducible. This is neither.

Where it goes

Today we predict. Next we design.

01 · Today

Predict

Rank every countermeasure that defeats a given genome.

Inputpathogen genome
Outputranked countermeasures
Modalityphages, peptides, proteins, small molecules
02 · Next

Design

Generate one when nothing on the shelf works.

Inputpathogen genome
Outputcandidate countermeasure
Modalityde novo, all modalities

One engine, every modality.

Who it's for

Hospitals and clinical labs

AI-bio and biopharma

Government biodefense

Get in touch

The response to biological threats should be predictable.

Pathogens, countermeasures, biosecurity — we'd like to hear from you.

jose.bila@subsira.bio Subsira Inc., Delaware San Francisco, US  ·  Lab: Lausanne, CH